Endocrine Abstracts

Background: Primary hyperparathyroidism (PHPT) is associated with various musculoskeletal complaints. It is difficult to evaluate muscle strength as it is hard to extract objective data due to lack of definite methods for measurement.Objective: To assess the differences between PHPT patients and healthy controls regarding maximum foot force and plantar pressure distribution by using platform pressure measuring system [Footscan (RSscan)].<p class="abs...

Objective: Different methods are used to identify individuals with insulin resistance. The gold standard is the euglycemic-hyperinsulinemic clamp. However, in clinical practice, clamp is not preferred because it is cumbersome, the HOMA-IR index is used more often. The Trigliserid-glucose (TyG) index is a new and practical way to identify individuals with insulin resistance (IR). When compared to HOMA-IR, this index has been shown to be more reliable in determining insulin resi...

Aim: The primary objective of this study was to evaluate the structural and functional cardiac parameters with MRI in patients with primary hyperparathyroidism (pHPT) before and after successful surgery.Method: In this prospective study 16 patients with pHPT were included. Detailed cardiac magnetic resonance imaging (MRI) examinations were performed preoperatively and at six months post-surgery. Following parameters were measured: Left ventricle ejection...

Objective: Thyroid cancer (TC) screening in acromegaly is a controversial topic. The Endocrine Society opposes routine TC screening in acromegaly patients without a palpable nodule, and the American Thyroid Association does not consider acromegaly to be a high-risk condition for developing TC. However, acromegaly is associated with an increased risk of TC, and some centers opt for thyroid ultrasound screening even in the absence of palpable thyroid nodules. Being one of the su...

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant genetic disorder characterized by parathyroid adenomas, enteropancreatic endocrine tumors and anterior pituitary adenomas. It is caused by inactivating mutations of the MEN1 tumor suppressor gene, encoding menin (chromosome 11q13). A large family with several members affected were evaluated for clinical and genetic characteristic of MEN1.The index male patient (42 yr) presented ...